“With new capital secured and active partnering discussions underway, we are positioned
to pursue the right deals and move these opportunities forward.”

Jeppe Øvlesen,
Chief Executive Officer

Second quarter 2026 (April – June)

• The Group’s net sales amounted to SEK 0 (0) thousand.
• Operating expenses amounted to SEK 24,556 (30,345) thousand, a decrease of 19%.
• The Group’s loss after tax amounted to SEK 22,032 (27,522) thousand.
• The Group’s earnings per share before and after dilution amounted to -0.39 (-0.56) SEK.
• Cash flow from operating activities amounted to SEK -34,541 (-18,788) thousand.
• Cash flow from financing activities amounted to SEK -3,082 (35,969) thousand.
• Cash flow for the period amounted to SEK -51,517 (17,181) thousand.
• Cash and cash equivalents at the end of the period amounted to SEK 14,288 (68,890) thousand.
  

First six months 2026 (January – June) 

• The Group’s net sales amounted to SEK 0 (0) thousand.
• Operating expenses amounted to SEK 55,113 (58,443) thousand, a decrease of 6%.
• The Group’s loss after tax amounted to SEK 47,519 (52,207) thousand.
• The Group’s earnings per share before and after dilution amounted to -0.87 (-1.07) SEK.
• Cash flow from operating activities amounted to SEK -67,492 (-47,614) thousand.
• Cash flow from financing activities amounted to SEK 42,225 (55,672) thousand.
• Cash flow for the period amounted to SEK -39,161 (8,058) thousand.
   

Significant events during the second quarter

• APR 23 – SynAct Pharma’s Nomination Committee ahead of the 2026 Annual General Meeting
• MAY 6 – SynAct Pharma completes dosing for last patient in Phase 2b ADVANCE study
• JUN 11 – Report from the 2026 Annual General Meeting of SynAct Pharma AB (publ)
• JUN 12 – SynAct obtains key US patent for resomelagon securing exclusivity until 2044
• JUN 15 – Phase 2b ADVANCE study demonstrates positive effects of resomelagon in Rheumatoid Arthritis – supports phase 3 design, regulatory interactions, and partnering and SynAct Pharma Board of Directors and Management Enter Lock-up Agreements
• JUN 29 – BIO International USA confirms growing interest in resomelagon and SynAct Pharma following the positive effects of the ADVANCE study
   

Significant events after the end of the period

• JUL 9 – Resomelagon shows reduced inflammation and joint damage in osteoarthritis model
• 20 JUL – SynAct Pharma strengthens financial position and strategic flexibility to advance partnering discussions and Phase III readiness
• AUG 5 – SynAct Pharma receives favorable US patent decision for immediate-release resomelagon tablet formulation
• AUG 19 – SynAct Pharma progresses first commercial agreement on resomelagon for treatment of dengue in Brazil – term sheet signed

The full report is attached as PDF and is available on the company’s website: https://www.synactpharma.com/en/investors/financial-reports/