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Analyst Comment

ExpreS2ion Biotechnologies: AdaptVac, Part of Consortium Receiving USD 12.4M in Grants

By Michael FriisHead of Equities
ExpreS2ion Biotech Holding

ExpreS2ion today announced that its associated company, AdaptVac (in which ExpreS2ion holds a 34% ownership), has been selected to lead a consortium that has been awarded a USD 12.4 million grant from CEPI and the European Union’s Horizon Europe Program. The grant will support the development of a novel vaccine designed to provide all-in-one protection against multiple deadly filoviruses. The project is expected to run over the next five years, including planned Phase I/II trials.

This announcement follows the latest news from AdaptVac, with an article published on May 14th in Nature Nanotechnology, titled "A Modular mRNA Vaccine Platform Encoding Antigen-Presenting Capsid Virus-Like Particles Enhances the Immunogenicity of the Malaria Antigen Pfs25." The study in mice demonstrated that by adding an additional genetic code to the current mRNA vaccine, the immune system could be stimulated to produce a stronger and longer-lasting response. This advancement could address the limitations of mRNA vaccines, particularly their inability to generate durable humoral immunity.

This breakthrough was also highlighted in a press release issued today and covered by several news outlets.

Read the press release here.

In our latest One-Pager analysis, one of the key investment reasons we highlighted is that ongoing news flow regarding partnership agreements and ExpreS2ion's ownership of AdaptVac may indicate that the market is undervaluing these assets.

Read the latest one-pager here:

https://www.inderes.dk/research/expres2ion-biotech-one-pager-pipeline-focus-on-her2-breast-cancer-therapy

Disclaimer: HC Andersen Capital receives payment from ExpreS2ion Biotechnologies for a Digital IR/Corporate Visibility subscription agreement. Michael Friis, 11:31, 19-06-2025

ExpreS2ion is a Danish-based biotech company listed in Sweden. The company develops a portfolio of vaccines for diseases such as COVID-19, influenza, and breast cancer through the use of its non-viral cell-based expression system, ExpreS2, which is recognized for handling protein challenges. ExpreS2ion has developed Expres2, which is a technology platform for efficient and fast non-clinical development and production of complex proteins for new vaccines and diagnostics. The company’s current primary product is the corona vaccine candidate, ABNCoV2 in phase 2, co-developed with its partner, AdaptVac of which ExpreS2ion owns 34%. The vaccine candidate has been licensed to Bavarian Nordic has global commercialization rights and responsibility for further clinical development of the vaccine and is expected to initiate phase 3 testing for the product candidate in the first half of 2022.

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