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Regulatory press release

VibroSense: New publication demonstrates strong correlation between Multi Frequency Vibrometry and Nerve Conduction Studies for diagnosis of nerve damage caused by diabetes.

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In a publication on Plos One,  (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0296661)the results of a clinical study were reported in which the company's technology Multi Frequency Vibrometry (MFV) was compared with Nerve Conduction Studies (NCS), which is generally regarded as the Gold Standard in the diagnosis of nerve damage caused by diabetes. The publication shows that there is a strong connection between MFV and NCS. For diabetes clinics, this means that they can provide Diabetic Foot Screening as an equivalent specialist examination (NCS), which is normally only performed in larger hospitals.

The article concludes, that there is a strong correlation between the amplitude of the sural nerve and vibration perception thresholds at 125 Hz. A further conclusion is that testing with MFV can be limited to only four frequencies instead of seven, shortening the testing time, to distinguish peripheral diabetic neuropathy in the lower extremity. The suggested frequencies are identical to those included in the company's instrument VibroSense Meter® II and the Diabetic Foot Screening examination.

"VibroSense technology Multi Frequency Vibrometry has been developed in close collaboration with clinical researchers and there is a huge potential in the diagnostics of peripheral neuropathy (nerve damage in the hands and feet). The recently published article is another important confirmation to achieve our vision The New Gold Standard for reliable detection of nerve damage", says Hans Wallin, CEO VibroSense Dynamics AB.

About Nerve Conduction Study

Nerve Conduction Study (NCS) is a non-invasive examination of the body's nerves. During the examination, surface electrodes are attached to the body which stimulate the nerves with electrical pulses. During the examination, both nerve conduction velocity and nerve conduction amplitude are measured. NCS is widely regarded as the Gold Standard in the diagnosis of nerve damage caused by diabetes. NCS is a so-called specialist examination that is normally only carried out in clinics for clinical physiology or neurophysiology in larger hospitals.

The examination is risk-free but can be perceived as unpleasant because the stimulation takes place through electric shocks. Abnormalities can be due to pressure on the nerves, but also to diseases such as diabetes or inflammatory conditions.

Contact
Hans Wallin, CEO VibroSense Dynamics AB
Tel: +46 40 88 026
Email: info@vibrosense.com
www.vibrosense.se

"The new Gold Standard for reliable
detection of nerve damage"

About VibroSense Dynamics AB (publ)
VibroSense Dynamics AB (publ) develops and sells medical technology products and services for diagnostic support for nerve damage in the hands and feet caused by, for example, diabetes, chemotherapy or vibrating hand-held tools. The method involves measuring and quantifying the ability to feel vibrations at several frequencies. The company's customers are diabetes clinics, occupational health care, hospitals, health centers and researchers.

Our vision is that the company's products should be a standard instrument in all neurological examinations to detect early signs of changes in sensation so that patients and their caregivers can implement preventive measures that prevent, reduce or delay the onset of nerve damage in the hands and feet.

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